Competences & Preclinical Research

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Services in preclinical research

Biopharmacy and Radiopharmaceutical Sciences at the ETH can offer the following services in preclinical research at small scale and at a limited capacity.

For further details contact:

PD Dr. Stefanie Kramer

ETH Zurich, Radiopharmaceutical Sciences / Biopharmacy

Institute of Pharmaceutical Sciences

Vladimir-Prelog Weg 4, 8093 Zurich, Switzerland

In vitro

  • Binding assays: IC50, Ki, KD
  • Autoradiography
  • Plasma protein binding
  • Cell culture
    Transport, uptake, efflux studies
    Identification of P-glycoprotein substrates, inhibitors

In vivo, ex vivo

  • Autoradiography
  • Pharmacokinetic studies with radiolabeled compounds
  • Pharmacokinetic analysis of clinical and preclinical data
  • Biodistribution of radiolabeled compounds
  • Xenograft models
  • PET/CT
    Kinetic modelling
    Displacement studies
    Receptor occupancy studies
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Tue Jul 25 12:31:31 CEST 2017
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